Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16202269 | 0.86 | KDM4E (0.42) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL8496598 | 0.78 | TAAR1 (0.50) | AOC3LMNAKDM4ERIPK1POLB | |
| SCHEMBL3746491 | 0.78 | RIPK1 (0.55) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL8027464 | 0.78 | RIPK1 (0.55) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL13507144 | 0.76 | KDM4E (0.60) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL8998258 | 0.74 | BCAT2 (0.49) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL9296142 | 0.74 | BCAT2 (0.49) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL12065087 | 0.73 | S1PR1 (0.44) | — | |
| SCHEMBL12435669 | 0.72 | RIPK1 (0.64) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL5163930 | 0.72 | RIPK1 (0.64) | AOC3LMNAKDM4EL3MBTL1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133096-B2 | Process for the production of 2-amino-2[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diols, and to compounds for use therein | NOVARTIS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| EP-2268603-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-2- [2- (4-C3-C21-ALKYL-PHENYL)ETHYL]PROPANE-1, 3-DIOLS | NOVARTIS AG (CH) | 2015-04-22 | — | — | EP | disclosed |
| US-8809571-B2 | Process for the production of 2-amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diols, and to compounds for use therein | NOVARTIS AG (CH) | 2014-08-19 | — | — | US | disclosed |