Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497911 | 1.00 | GAA (0.50) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8497057 | 0.91 | GAA (0.43) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8497059 | 0.91 | GAA (0.43) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8498152 | 0.87 | G6PC1 (0.54) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8498042 | 0.86 | ATM (0.59) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8498045 | 0.86 | ATM (0.59) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8497145 | 0.86 | MEN1 (0.52) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8497147 | 0.86 | MEN1 (0.52) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8498741 | 0.84 | MEN1 (0.41) | GAAMAPTATMG6PC1ALDH1A1 | |
| SCHEMBL8497170 | 0.82 | ACHE (0.48) | GAAMAPTG6PC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |