Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498487 | 1.00 | KDM4E (0.48) | KDM4EHPGDNR1I2KMT2ACES2 | |
| SCHEMBL8495082 | 0.90 | G6PC1 (0.46) | KDM4EHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8495078 | 0.90 | G6PC1 (0.46) | KDM4EHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8499190 | 0.87 | KDM4E (0.47) | KDM4EHPGDNR1I2KMT2ACES2 | |
| SCHEMBL8499194 | 0.87 | KDM4E (0.47) | KDM4EHPGDNR1I2KMT2ACES2 | |
| SCHEMBL8498045 | 0.85 | ATM (0.59) | KDM4EHPGDKMT2ACES2CES1 | |
| SCHEMBL8498042 | 0.85 | ATM (0.59) | KDM4EHPGDKMT2ACES2CES1 | |
| SCHEMBL8497170 | 0.82 | ACHE (0.48) | KDM4EHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8497173 | 0.82 | ACHE (0.48) | KDM4EHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8655031 | 0.81 | KDM4E (0.53) | KDM4EHPGDKMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | claimed |