Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429000 | 0.80 | MEN1 (0.53) | CXCR3MEN1KMT2ASMYD3 | |
| SCHEMBL6547215 | 0.79 | PRCP (0.42) | MEN1KMT2AKEAP1HDAC3HDAC11 | |
| SCHEMBL11657213 | 0.79 | PRCP (0.42) | MEN1KMT2AKEAP1HDAC3HDAC11 | |
| SCHEMBL11174438 | 0.79 | PRCP (0.42) | MEN1KMT2AKEAP1HDAC3HDAC11 | |
| SCHEMBL29630736 | 0.79 | KEAP1 (0.39) | MEN1KMT2AKEAP1HDAC3HDAC11 | |
| SCHEMBL6384470 | 0.78 | KEAP1 (0.48) | KEAP1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL29924267 | 0.78 | PRCP (0.41) | MEN1KMT2AKEAP1HDAC3HDAC11 | |
| SCHEMBL29548137 | 0.78 | PRCP (0.41) | MEN1KMT2AKEAP1HDAC3HDAC11 | |
| SCHEMBL11657224 | 0.77 | PRCP (0.41) | CXCR3 | |
| SCHEMBL29489137 | 0.77 | KEAP1 (0.39) | MEN1KMT2AKEAP1HDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999022758-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1999-05-14 | — | — | WO | disclosed |