Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GALR3 | O60755 | 2/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506287 | 0.82 | HTT (0.59) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL29898477 | 0.82 | LMNA (0.75) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL1520577 | 0.82 | LMNA (0.75) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL29898476 | 0.82 | LMNA (0.75) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL13283188 | 0.79 | L3MBTL1 (0.65) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL9608005 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL10339204 | 0.77 | LMNA (0.97) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL4980648 | 0.76 | EGFR (0.62) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL12199178 | 0.75 | SMN1; SMN2 (0.77) | SMN1; SMN2LMNAHTTMAPTKMT2A | |
| SCHEMBL8489605 | 0.75 | LMNA (0.58) | SMN1; SMN2LMNAHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |