⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825498 | 0.73 | — | — | |
| SCHEMBL10548828 | 0.73 | — | — | |
| Oxalic Acid SCHEMBL11791667 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL9768250 | 0.65 | — | — | |
| SCHEMBL6185249 | 0.62 | POLB (0.34) | — | |
| SCHEMBL613869 | 0.61 | CTSK (0.32) | — | |
| SCHEMBL94144 | 0.61 | CTSK (0.32) | — | |
| SCHEMBL94143 | 0.61 | CTSK (0.32) | — | |
| SCHEMBL23825481 | 0.60 | — | — | |
| SCHEMBL379775 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586663-B1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LTD (GB) | 1999-09-29 | — | — | EP | disclosed |
| US-5519015-A | BACTERICIDES | ZENECA LIMITED (GB) | 1996-05-21 | — | — | US | disclosed |
| EP-0586663-A1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993019070-A1 | CARBAPENEM DERIVATIVES AS ANTIBIOTICS AND INTERMEDIATES THEREOF | ZENECA LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |