Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27373175 | 0.89 | SIGMAR1 (0.37) | SIGMAR1KMT2AHTR2AOPRD1POLB | |
| SCHEMBL27784454 | 0.76 | KMT2A (0.39) | SIGMAR1KMT2AHTR2AOPRD1POLB | |
| SCHEMBL8109695 | 0.74 | SIGMAR1 (0.39) | SIGMAR1KMT2AHTR2AOPRD1POLB | |
| SCHEMBL5188679 | 0.73 | KMT2A (0.34) | SIGMAR1KMT2AOPRD1OPRM1ALDH1A1 | |
| SCHEMBL14833467 | 0.72 | SIGMAR1 (0.38) | SIGMAR1KMT2AHTR2AOPRD1POLB | |
| SCHEMBL27662588 | 0.71 | SLC6A2 (0.41) | OPRD1OPRL1 | |
| SCHEMBL18284816 | 0.71 | SIGMAR1 (0.39) | SIGMAR1KMT2AHTR2AOPRD1POLB | |
| SCHEMBL4759637 | 0.69 | HTR2A (0.38) | SIGMAR1KMT2AHTR2AOPRD1POLB | |
| SCHEMBL8499541 | 0.69 | POLB (0.35) | KMT2APOLBUSP2ALDH1A1TSHR | |
| SCHEMBL2404059 | 0.69 | SIGMAR1 (0.35) | SIGMAR1KMT2AHTR2AOPRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |