Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599372 | 0.74 | CHRM1 (0.36) | POLBKDM4EALDH1A1CHRM1TACR1 | |
| SCHEMBL15094650 | 0.74 | CHRM1 (0.36) | POLBKDM4EALDH1A1CHRM1TACR1 | |
| SCHEMBL8499176 | 0.69 | SIGMAR1 (0.36) | POLBALDH1A1USP2TSHRKMT2A | |
| SCHEMBL27749273 | 0.64 | ALDH1A1 (0.36) | KDM4EALDH1A1CHRM1TACR1MEN1 | |
| SCHEMBL5662090 | 0.64 | OPRL1 (0.33) | POLBMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL16599371 | 0.63 | GAA (0.36) | SLC6A2SLC6A4SLC6A3GAA | |
| SCHEMBL11883519 | 0.63 | SLC18A3 (0.36) | POLBKDM4EALDH1A1MEN1TSHR | |
| SCHEMBL15094674 | 0.62 | CHRNB2 (0.36) | POLBSLC6A2SLC6A4SLC6A3GAA | |
| SCHEMBL2913724 | 0.61 | POLB (0.42) | POLBKDM4EALDH1A1MEN1TSHR | |
| SCHEMBL16598947 | 0.61 | GAA (0.35) | ALDH1A1CHRM1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |