Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499202 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AACHEGAA | |
| SCHEMBL8497154 | 0.87 | MAPT (0.43) | ALDH1A1MAPTKMT2AACHEGAA | |
| SCHEMBL8497157 | 0.87 | MAPT (0.43) | ALDH1A1MAPTKMT2AACHEGAA | |
| SCHEMBL8498475 | 0.85 | G6PC1 (0.54) | ALDH1A1MAPTKMT2AACHELTA4H | |
| SCHEMBL8498477 | 0.85 | G6PC1 (0.54) | ALDH1A1MAPTKMT2AACHELTA4H | |
| SCHEMBL8498652 | 0.83 | L3MBTL1 (0.50) | ALDH1A1MAPTKMT2AACHEGAA | |
| SCHEMBL8498654 | 0.83 | L3MBTL1 (0.50) | ALDH1A1MAPTKMT2AACHEGAA | |
| SCHEMBL8498217 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AGAALTA4H | |
| SCHEMBL8498219 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AGAALTA4H | |
| SCHEMBL8498826 | 0.81 | G6PC1 (0.44) | ALDH1A1MAPTKMT2AACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |