Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498096 | 0.95 | ESR1 (0.48) | ESR1ESR2RAB9AKMT2A | |
| SCHEMBL8499778 | 0.92 | ESR1 (0.54) | ESR1ESR2RAB9AKMT2A | |
| SCHEMBL8502300 | 0.90 | ESR1 (0.56) | ESR1ESR2BCL9CTNNB1 | |
| SCHEMBL8497550 | 0.87 | ESR1 (0.49) | ESR1ESR2RAB9AKMT2A | |
| SCHEMBL8497879 | 0.86 | KMT2A (0.42) | ESR1ESR2BCL9CTNNB1RAB9A | |
| SCHEMBL8500225 | 0.86 | ESR1 (0.48) | ESR1ESR2KMT2A | |
| SCHEMBL8497867 | 0.86 | ESR1 (0.57) | ESR1ESR2 | |
| SCHEMBL7182784 | 0.85 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL8501462 | 0.84 | ESR1 (0.47) | ESR1ESR2KMT2A | |
| SCHEMBL8501283 | 0.84 | ESR1 (0.52) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | claimed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |