Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498114 | 0.94 | ESR1 (0.46) | ESR1ESR2MAOAMAOB | |
| SCHEMBL8497260 | 0.94 | ESR1 (0.55) | ESR1ESR2 | |
| SCHEMBL8497565 | 0.94 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL8501397 | 0.91 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL8500428 | 0.90 | ESR1 (0.41) | ESR1ESR2 | |
| SCHEMBL8501042 | 0.86 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL8499778 | 0.85 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL8499330 | 0.84 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL7189521 | 0.83 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL8501225 | 0.83 | ESR1 (0.43) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | claimed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |