SCHEMBL8499385

SCHEMBL8499385

Cc1cccc(N(c2cccc(C)c2)c2cccc(O)c2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.64
ALDH1A1 P00352 4/20 0.57
TSHR P16473 1/20 0.57
CYP3A4 P08684 2/20 0.52
HSD17B1 P14061 4/20 0.44
HSD17B2 P37059 4/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
LMNA P02545 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
SIGMAR1 Q99720 2/20 0.41
ADRA1A P35348 4/20 0.39
ADRA2A P08913 3/20 0.39
ADRA1D P25100 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3099000 1.00 ACHE (0.64) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL7875127 0.94 ACHE (0.57) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL7654504 0.93 ACHE (0.55) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL19192998 0.91 ACHE (0.53) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL2609916 0.88 ACHE (0.50) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL2609917 0.88 ACHE (0.50) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL31256035 0.87 ALDH1A1 (0.65) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL2355267 0.87 ALDH1A1 (0.65) ACHEALDH1A1TSHRCYP3A4HSD17B1
SCHEMBL977663 0.87 ACHE (0.58) ACHEALDH1A1CYP3A4HSD17B1HSD17B2
SCHEMBL9436732 0.86 ALDH1A1 (0.55) ACHEALDH1A1TSHRCYP3A4HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919608-A EXPOSING TO ELECTROMAGNETIC RADIATION A COMPOSITION COMPRISING CATIONIC ELECTRON ACCEPTOR, SENSITIZING DYE, AND SUPERSENSITIZER POLAROID CORPORATION (US) 1999-07-06 US disclosed