SCHEMBL2609916

SCHEMBL2609916

Cc1cccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4cccc(O)c4)cc3)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 2/20 0.46
TSHR P16473 1/20 0.46
HSD17B1 P14061 9/20 0.42
HSD17B2 P37059 9/20 0.42
CYP2C9 P11712 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
OPRD1 P41143 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NPC1 O15118 1/20 0.38
JAK2 O60674 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609917 1.00 ACHE (0.50) ACHEALDH1A1CYP3A4TSHRHSD17B1
SCHEMBL19192998 0.97 ACHE (0.53) ACHEALDH1A1CYP3A4TSHRHSD17B1
SCHEMBL7875127 0.93 ACHE (0.57) ACHEALDH1A1CYP3A4TSHRHSD17B1
SCHEMBL12268827 0.92 MMP3 (0.45) ACHEALDH1A1HSD17B1HSD17B2POLB
SCHEMBL10064828 0.92 MMP3 (0.45) ACHEALDH1A1HSD17B1HSD17B2POLB
SCHEMBL15315168 0.92 MMP3 (0.45) ACHEALDH1A1HSD17B1HSD17B2POLB
SCHEMBL223856 0.90 HSD17B1 (0.50) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL913348 0.90 HSD17B1 (0.50) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL504209 0.90 HSD17B1 (0.50) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL8581884 0.90 HSD17B1 (0.45) ACHEALDH1A1CYP3A4TSHRHSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210364938-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS EQUIPPED THEREWITH SHARP KABUSHIKI KAISHA (JP) 2021-11-25 US disclosed
US-8815481-B2 Imaging member with fluorosulfonamide-containing overcoat layer XEROX CORPORATION (US) 2014-08-26 US disclosed
US-8765342-B2 Photoconductors XEROX CORPORATION (US) 2014-07-01 US disclosed
US-20140127616-A1 PHOTOCONDUCTORS XEROX CORPORATION (US) 2014-05-08 US disclosed
US-8715896-B2 Polyalkylene glycol benzoate containing photoconductors XEROX CORPORATION (US) 2014-05-06 US disclosed
US-20140087298-A1 IMAGING MEMBER WITH FLUOROSULFONAMIDE-CONTAINING OVERCOAT LAYER XEROX CORPORATION (US) 2014-03-27 US disclosed
US-8660465-B2 Surface-patterned photoreceptor XEROX CORPORATION (US) 2014-02-25 US disclosed
US-8507161-B2 Phenolic phosphite containing photoconductors XEROX CORPORATION (US) 2013-08-13 US disclosed
US-8377615-B2 Photoconductors containing charge transporting polycarbonates XEROX CORPORATION (US) 2013-02-19 US disclosed
US-20130017479-A1 PHENOLIC PHOSPHITE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2013-01-17 US disclosed
US-20080299472-A1 Photoconductors XEROX CORPORATION 2008-12-04 US disclosed
US-20080193866-A1 Polyhydroxy siloxane photoconductors XEROX CORPORATION 2008-08-14 US disclosed
US-20080107983-A1 Overcoated photoconductors with thiophosphate containing photogenerating layer XEROX CORPORATION 2008-05-08 US disclosed
US-20080107984-A1 Overcoated photoconductors with thiophosphate containing charge transport layers XEROX CORPORATION 2008-05-08 US disclosed
US-20080107985-A1 Silanol containing overcoated photoconductors XEROX CORPORATION 2008-05-08 US disclosed
US-20080107979-A1 Silanol containing charge transport overcoated photoconductors XEROX CORPORATION 2008-05-08 US disclosed
US-20080014518-A1 Process for preparing photosensitive outer layer XEROX CORPORATION (US) 2008-01-17 US disclosed
US-20080003513-A1 Process for preparing photosensitive outer layer XEROX CORPORATION (US) 2008-01-03 US disclosed
US-7297456-B2 Photoconductors containing crosslinked polycarbonate polymers XEROX CORPORATION (US) 2007-11-20 US disclosed
US-7229732-B2 Imaging members with crosslinked polycarbonate in charge transport layer XEROX CORPORATION (US) 2007-06-12 US disclosed