Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843337 | 0.88 | FFAR1 (0.34) | PTGESFFAR1ALDH1A1LMNAMAPT | |
| SCHEMBL3583057 | 0.76 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL28722248 | 0.75 | OPRM1 (0.39) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8500799 | 0.75 | FFAR1 (0.41) | FFAR1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8525559 | 0.74 | FFAR1 (0.33) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL8663991 | 0.73 | FFAR1 (0.34) | FFAR1ALDH1A1LMNAMAPTCYP1A2 | |
| SCHEMBL8525878 | 0.73 | RXRA (0.33) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL8501575 | 0.72 | FFAR1 (0.37) | PTGESFFAR1ALDH1A1LMNAMAPT | |
| SCHEMBL8526230 | 0.71 | FFAR1 (0.32) | FFAR1LMNACYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL11761426 | 0.70 | FFAR1 (0.38) | FFAR1ALDH1A1LMNAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927156-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998009940-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |