Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 6/20 | 0.32 |
| ▸ | RXRB | P28702 | 6/20 | 0.32 |
| ▸ | RXRG | P48443 | 6/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499418 | 0.88 | PTGES (0.34) | FFAR1CYP1A2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8663991 | 0.82 | FFAR1 (0.34) | FFAR1CYP1A2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8525559 | 0.81 | FFAR1 (0.33) | FFAR1CYP1A2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8525878 | 0.80 | RXRA (0.33) | FFAR1CYP1A2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8526230 | 0.80 | FFAR1 (0.32) | FFAR1CYP1A2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3583057 | 0.78 | MEN1 (0.31) | MEN1KMT2ATDP1 | |
| SCHEMBL8500799 | 0.77 | FFAR1 (0.41) | FFAR1SMN1; SMN2MEN1KMT2ARXRA | |
| SCHEMBL8526445 | 0.76 | FFAR1 (0.32) | FFAR1CYP1A2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11761426 | 0.72 | FFAR1 (0.38) | FFAR1CYP1A2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28722248 | 0.72 | OPRM1 (0.39) | SMN1; SMN2MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176393-A1 | Statin-MMP inhibitor combinations | NEWTON ROGER SCHOFIELD (US) | 2004-09-09 | — | — | US | disclosed |
| EP-0927156-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998009940-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176393-A1 | Statin-MMP inhibitor combinations | MMP9, TIMP3, MMP3 | FFAR1 1763/4885CYP1A2 666/4885LMNA 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.