Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201212 | 0.79 | ACACB (0.41) | ACACB | |
| SCHEMBL7148778 | 0.72 | ADRB3 (0.65) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7148774 | 0.72 | ADRB3 (0.65) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7937104 | 0.71 | ADRB2 (0.75) | ADRB3ADRB1ADRB2ADRA1ACYP1A2 | |
| SCHEMBL7149113 | 0.71 | ADRB2 (0.75) | ADRB3ADRB1ADRB2ADRA1ACYP1A2 | |
| SCHEMBL7149115 | 0.71 | ADRB2 (0.75) | ADRB3ADRB1ADRB2ADRA1ACYP1A2 | |
| SCHEMBL7153455 | 0.70 | ADRB2 (0.72) | ADRB3ADRB1ADRB2ADRA1ACYP1A2 | |
| SCHEMBL7049980 | 0.70 | ADRB2 (0.72) | ADRB3ADRB1ADRB2ADRA1ACYP1A2 | |
| SCHEMBL7153454 | 0.70 | ADRB2 (0.72) | ADRB3ADRB1ADRB2ADRA1ACYP1A2 | |
| SCHEMBL20354241 | 0.70 | PDE4A (0.48) | ADRB3ADRB1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924194-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |