Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499680 | 0.79 | ADRB3 (0.51) | ACACB | |
| SCHEMBL7399544 | 0.73 | ALDH1A1 (0.46) | ACACBSMN1; SMN2 | |
| SCHEMBL22252465 | 0.72 | P2RX7 (0.54) | — | |
| SCHEMBL26197517 | 0.71 | CA1 (0.40) | PARP10FURINSMN1; SMN2 | |
| SCHEMBL24288059 | 0.71 | ACACB (0.46) | ACACBPARP10FFAR1 | |
| SCHEMBL10148464 | 0.70 | ALDH1A1 (0.51) | — | |
| SCHEMBL10148461 | 0.70 | SMN1; SMN2 (0.47) | PARP10FURINHPGDSMN1; SMN2 | |
| SCHEMBL10148472 | 0.70 | SMN1; SMN2 (0.47) | PARP10FURINHPGDSMN1; SMN2 | |
| SCHEMBL10148457 | 0.70 | ALDH1A1 (0.51) | — | |
| SCHEMBL29908033 | 0.69 | SLCO1B1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |