Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895319 | 0.83 | MAPT (0.59) | ALDH1A1LMNAMAPTHSD17B10HTT | |
| SCHEMBL8351588 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL11327422 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTHSD17B10HTT | |
| SCHEMBL8351721 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL10373263 | 0.80 | ALDH1A1 (0.61) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL14192707 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAGFERMEN1 | |
| SCHEMBL215500 | 0.79 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL594488 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAGFERMEN1 | |
| SCHEMBL8957639 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAGFERMEN1 | |
| SCHEMBL1186097 | 0.76 | LMNA (0.58) | ALDH1A1LMNAGAAGFERMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |