Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499831 | 1.00 | KDM4E (0.47) | KDM4ERECQLALDH1A1KMT2AGAA | |
| SCHEMBL8499167 | 0.84 | ALDH1A1 (0.50) | KDM4ERECQLALDH1A1KMT2AGAA | |
| SCHEMBL8499169 | 0.84 | ALDH1A1 (0.50) | KDM4ERECQLALDH1A1KMT2AGAA | |
| SCHEMBL8498249 | 0.80 | GAA (0.51) | KDM4ERECQLALDH1A1KMT2AGAA | |
| SCHEMBL8498244 | 0.80 | GAA (0.51) | KDM4ERECQLALDH1A1KMT2AGAA | |
| SCHEMBL19966697 | 0.78 | ATM (0.36) | ALDH1A1KMT2AKEAP1TAAR1SIGMAR1 | |
| SCHEMBL27577810 | 0.74 | LMNA (0.42) | ALDH1A1KMT2ALMNA | |
| SCHEMBL24834896 | 0.74 | ALDH1A1 (0.57) | KDM4ERECQLALDH1A1KMT2AKEAP1 | |
| SCHEMBL5593707 | 0.74 | ALDH1A1 (0.57) | KDM4ERECQLALDH1A1KMT2AKEAP1 | |
| SCHEMBL2551920 | 0.74 | ALDH1A1 (0.57) | KDM4ERECQLALDH1A1KMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |