Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498249 | 1.00 | GAA (0.51) | GAAMAPTKDM4ERECQLKMT2A | |
| SCHEMBL8499167 | 0.81 | ALDH1A1 (0.50) | GAAKDM4ERECQLKMT2AALDH1A1 | |
| SCHEMBL8499169 | 0.81 | ALDH1A1 (0.50) | GAAKDM4ERECQLKMT2AALDH1A1 | |
| SCHEMBL8499830 | 0.80 | KDM4E (0.47) | GAAKDM4ERECQLKMT2AALDH1A1 | |
| SCHEMBL8499831 | 0.80 | KDM4E (0.47) | GAAKDM4ERECQLKMT2AALDH1A1 | |
| SCHEMBL8499655 | 0.76 | GAA (0.35) | GAAMAPTKDM4ERECQLKMT2A | |
| SCHEMBL8499201 | 0.74 | ALDH1A1 (0.46) | GAAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL8499202 | 0.74 | ALDH1A1 (0.46) | GAAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL14799383 | 0.72 | G6PC1 (0.65) | KMT2AALDH1A1MEN1G6PC1LMNA | |
| SCHEMBL14799382 | 0.72 | G6PC1 (0.65) | KMT2AALDH1A1MEN1G6PC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | claimed |
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |