Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236527 | 0.73 | KDM4E (0.40) | KCNN4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8499551 | 0.73 | SIRT2 (0.42) | KCNN4SIRT2 | |
| SCHEMBL8499957 | 0.71 | L3MBTL1 (0.40) | KCNN4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7412278 | 0.71 | L3MBTL1 (0.40) | KCNN4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL2233946 | 0.70 | KCNN4 (0.36) | KCNN4MEN1KMT2AKDM4ETSHR | |
| SCHEMBL1424040 | 0.70 | CDC25B (0.47) | MEN1KMT2AKDM4EHPGDTSHR | |
| SCHEMBL10439557 | 0.70 | CYP11B1 (0.37) | KCNN4MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL10439558 | 0.69 | CYP1A2 (0.44) | KCNN4MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7534704 | 0.69 | HIF1A (0.37) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL9756933 | 0.67 | MEN1 (0.37) | KCNN4MEN1KMT2ASIRT2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932606-A | Pyrazinone, pyridinone, piperidine and pyrrolidine thrombin inhibitors | MERCK & CO., INC. (US) | 1999-08-03 | — | — | US | disclosed |