Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502205 | 0.93 | MTNR1A (0.43) | TDP1L3MBTL1MTNR1AMTNR1BGPR84 | |
| SCHEMBL8497554 | 0.89 | L3MBTL1 (0.51) | TDP1L3MBTL1GPR84TP53MAPT | |
| SCHEMBL8500568 | 0.89 | ESR1 (0.48) | MTNR1AMTNR1BTHRATHRB | |
| SCHEMBL8500292 | 0.88 | ESR1 (0.47) | TDP1L3MBTL1THRATHRBTP53 | |
| SCHEMBL8501340 | 0.88 | ELANE (0.48) | TDP1L3MBTL1TP53MAPTELANE | |
| SCHEMBL8497702 | 0.85 | ESR1 (0.49) | MTNR1AMTNR1BCYP1A2THRATHRB | |
| SCHEMBL8497439 | 0.85 | ESR1 (0.49) | MTNR1AMTNR1BDGAT2AKR1C3AKR1C2 | |
| SCHEMBL6050235 | 0.83 | MIF (0.46) | GPR84CYP1A1CYP1A2CYP1B1BRD4 | |
| SCHEMBL8500300 | 0.82 | CYP1A2 (0.40) | TDP1L3MBTL1MTNR1AMTNR1BGPR84 | |
| SCHEMBL8501206 | 0.82 | MAPT (0.45) | TDP1L3MBTL1TP53MAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |