Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500468 | 1.00 | TNNC1 (0.46) | TNNC1PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL27892640 | 0.90 | PPARA (0.53) | TNNC1PPARAPPARGLPLLIPG | |
| SCHEMBL8436682 | 0.89 | TNNC1 (0.49) | TNNC1PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL8437030 | 0.89 | PPARA (0.50) | TNNC1PPARAPPARGLPLLIPG | |
| SCHEMBL28801237 | 0.88 | PPARA (0.51) | TNNC1PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL8436465 | 0.87 | TNNC1 (0.47) | TNNC1PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL9836116 | 0.87 | PPARA (0.50) | TNNC1PPARAPPARGLPLLIPG | |
| Ammonia Solution, Strong SCHEMBL27776409 | 0.87 | PPARA (0.44) | TNNC1PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL9836110 | 0.87 | PPARA (0.50) | TNNC1PPARAPPARGLPLLIPG | |
| SCHEMBL8498447 | 0.86 | CYP4F2 (0.54) | TNNC1PPARAPPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |