Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714742 | 0.95 | NPSR1 (0.39) | NPSR1UTS2RMTNR1AMTNR1BCARM1 | |
| SCHEMBL8502237 | 0.93 | NPSR1 (0.38) | NPSR1UTS2RDRD2CHRM1 | |
| SCHEMBL8665880 | 0.91 | UTS2R (0.39) | NPSR1UTS2RMTNR1AMTNR1BCARM1 | |
| SCHEMBL8666092 | 0.89 | UTS2R (0.39) | NPSR1UTS2RMTNR1AMTNR1BCARM1 | |
| SCHEMBL8485533 | 0.86 | NPSR1 (0.42) | NPSR1UTS2RCARM1PRMT6DRD2 | |
| SCHEMBL8501233 | 0.84 | NPSR1 (0.36) | NPSR1UTS2RDRD2DRD4CHRM1 | |
| SCHEMBL8484454 | 0.84 | NPSR1 (0.42) | NPSR1UTS2RCARM1PRMT6DRD2 | |
| SCHEMBL8501048 | 0.82 | NPSR1 (0.35) | NPSR1UTS2RCHRM1 | |
| SCHEMBL8665515 | 0.81 | CCR3 (0.41) | NPSR1MTNR1AMTNR1BDRD2 | |
| SCHEMBL8664869 | 0.80 | SMPD3 (0.38) | MTNR1AMTNR1BCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |