Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 4/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1274109 | 0.90 | SLC6A5 (0.50) | HDAC6 | |
| Trifluoroacetic Acid SCHEMBL1273878 | 0.90 | SLC6A5 (0.50) | HDAC6 | |
| Trifluoroacetic Acid SCHEMBL8501095 | 0.88 | HDAC6 (0.58) | HDAC6PAOXEPHX1RELAS1PR1 | |
| SCHEMBL6843614 | 0.85 | TDP1 (0.53) | RELATDP1 | |
| Trifluoroacetic Acid SCHEMBL3086371 | 0.84 | FAAH (0.43) | EPHX1KDM5APHF8KDM4C | |
| Hydrochloric Acid SCHEMBL5540229 | 0.83 | UBE2N (0.52) | RELATDP1 | |
| SCHEMBL11315437 | 0.83 | TDP1 (0.55) | EPHX1RELATDP1 | |
| SCHEMBL11332828 | 0.83 | TDP1 (0.55) | EPHX1RELATDP1 | |
| SCHEMBL27853903 | 0.82 | TDP1 (0.53) | EPHX1RELATDP1 | |
| SCHEMBL8504211 | 0.82 | RELA (0.50) | RELATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202227-B2 | Multifunctional molecular complexes for gene transfer to cells | WYETH (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050239204-A1 | Multifunctional molecular complexes for gene transfer to cells | WYETH (US) | 2005-10-27 | — | — | US | disclosed |
| EP-0789708-B1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | WYETH CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040214328-A9 | Multifunctional molecular complexes for gene transfer to cells | AMERICAN HOME PRODUCTS CORPORATION (US) | 2004-10-28 | — | — | US | disclosed |
| US-20020155607-A1 | Multifunctional molecular complexes for gene transfer to cells | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-10-24 | — | — | US | disclosed |
| US-6379965-B1 | NUCLEIC ACID NONCOVALENTLY ASSOCIATED WITH A POLYAMINE COMPOUND THAT IS COVALENTLY ATTACHED TO AN ENDOSOME DISRUPTING AGENT SUCH AS CHOLIC ACID; NONVIRAL VECTORS | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214328-A9 | Multifunctional molecular complexes for gene transfer to cells | SNRPE, TARBP1, HNRNPH3 | HDAC6 2504/4885PAOX 3374/4885EPHX1 4423/4885 |
| US-20020155607-A1 | Multifunctional molecular complexes for gene transfer to cells | SNRPE, TARBP1, HNRNPH3 | HDAC6 2504/4885PAOX 3374/4885EPHX1 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.