Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | C1S | P09871 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905131 | 0.75 | MEN1 (0.47) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL8500969 | 0.74 | KMT2A (0.46) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL8503418 | 0.67 | MEN1 (0.45) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL8497829 | 0.66 | KMT2A (0.44) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL28725485 | 0.65 | LMNA (0.56) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL537030 | 0.64 | LMNA (0.77) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL12248115 | 0.63 | ESR1 (0.52) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL20714999 | 0.62 | PRSS1 (0.44) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL1445807 | 0.62 | PRSS1 (0.53) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL1445939 | 0.62 | PRSS1 (0.48) | PRSS1PRSS3PRSS2F10LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811398-A | Platelet aggregation inhibitors containing C-terminal aminergic side chain amino acid residues | G. D. SEARLE & CO. (US) | 1998-09-22 | — | — | US | claimed |
| US-5886208-A | Substituted B-amino acid derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5811398-A | Platelet aggregation inhibitors containing C-terminal aminergic side chain amino acid residues | G. D. SEARLE & CO. (US) | 1998-09-22 | — | — | US | disclosed |