Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8497829 | 0.99 | KMT2A (0.44) | MEN1CYP1A2KMT2AF2PRSS1 | |
| SCHEMBL8905131 | 0.85 | MEN1 (0.47) | MEN1CYP1A2KMT2AF2PRSS1 | |
| Hydrochloric Acid SCHEMBL8500969 | 0.84 | KMT2A (0.46) | MEN1CYP1A2KMT2AF2PRSS1 | |
| SCHEMBL6011852 | 0.78 | MEN1 (0.73) | MEN1CYP1A2KMT2AF2PRSS1 | |
| SCHEMBL8503420 | 0.75 | MEN1 (0.38) | MEN1CYP1A2KMT2AGRM5GRM1 | |
| Hydrochloric Acid SCHEMBL8497837 | 0.74 | MEN1 (0.37) | MEN1CYP1A2KMT2A | |
| SCHEMBL27403702 | 0.69 | F2 (0.47) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL10604183 | 0.69 | NQO2 (0.51) | MEN1CYP1A2KMT2AF2PRSS1 | |
| SCHEMBL1445807 | 0.67 | PRSS1 (0.53) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8501113 | 0.67 | PRMT5 (0.38) | F2PRSS1PRSS2PRSS3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886208-A | Substituted B-amino acid derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5703125-A | MELT BLEND OF SOAP, SURFACTANT AND SOLVENT | G. D. SEARLE & CO. (US) | 1997-12-30 | — | — | US | disclosed |