Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502011 | 0.83 | SMN1; SMN2 (0.39) | MEN1HTTKMT2AL3MBTL1KCNA5 | |
| SCHEMBL8502297 | 0.78 | AOC3 (0.43) | MEN1HTTKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8505045 | 0.77 | AOC3 (0.42) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1529633 | 0.77 | KMT2A (0.54) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL8648237 | 0.76 | AOC3 (0.43) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL8504370 | 0.75 | AOC3 (0.42) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL8502790 | 0.74 | MEN1 (0.44) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL8239858 | 0.71 | CTSK (0.56) | AKT1CTSSCTSKCTSLCTSB | |
| SCHEMBL4669797 | 0.70 | CTSK (0.44) | AKT1CTSSCTSKL3MBTL1 | |
| SCHEMBL8505244 | 0.69 | ALDH1A1 (0.40) | MEN1HTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872298-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5872299-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5831117-A | ACID SALTS | G. D. SEARLE & CO. (US) | 1998-11-03 | — | — | US | disclosed |