Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.40 |
| ▸ | ITGAV | P06756 | 14/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.40 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501217 | 0.84 | ITGB3 (0.45) | ITGB3ITGAVITGA2BCBLB | |
| SCHEMBL7864766 | 0.81 | ITGB3 (0.38) | ITGB3ITGAVITGA2BCTSAFFAR1 | |
| SCHEMBL7864160 | 0.78 | FFAR1 (0.39) | ITGB3ITGAVITGA2BCTSAFFAR1 | |
| SCHEMBL7866947 | 0.77 | PTPN11 (0.41) | CTSAFFAR1 | |
| SCHEMBL7866927 | 0.75 | FFAR1 (0.45) | ITGB3ITGAVFFAR1 | |
| SCHEMBL7856436 | 0.75 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL7457204 | 0.73 | ITGB3 (0.53) | ITGB3ITGA2BFFAR1 | |
| SCHEMBL7863123 | 0.73 | ITGB3 (0.39) | ITGB3ITGAVCTSA | |
| SCHEMBL7863159 | 0.73 | KMT2A (0.56) | CTSAFFAR1 | |
| SCHEMBL7864712 | 0.72 | SIRT2 (0.45) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997036862-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |