Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CTSA | P10619 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864160 | 0.85 | FFAR1 (0.39) | KMT2ASMN1; SMN2CTSAFFAR1 | |
| SCHEMBL7863151 | 0.84 | KMT2A (0.57) | KMT2ASMN1; SMN2CTSAFFAR1SGMS2 | |
| SCHEMBL7866927 | 0.82 | FFAR1 (0.45) | FFAR1MRGPRX4 | |
| SCHEMBL7866947 | 0.79 | PTPN11 (0.41) | KMT2ACTSAFFAR1 | |
| SCHEMBL7863123 | 0.77 | ITGB3 (0.39) | KMT2ACTSA | |
| SCHEMBL7864766 | 0.77 | ITGB3 (0.38) | KMT2ACTSAFFAR1 | |
| SCHEMBL7864712 | 0.76 | SIRT2 (0.45) | NR1H4SIRT2 | |
| SCHEMBL7861983 | 0.76 | CTSA (0.33) | KMT2ASMN1; SMN2CTSAFFAR1 | |
| SCHEMBL7856436 | 0.75 | ITGB3 (0.48) | KMT2ASMN1; SMN2NR1H4 | |
| SCHEMBL7863191 | 0.75 | KMT2A (0.47) | KMT2ASMN1; SMN2CTSAFFAR1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0889877-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997036862-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |