SCHEMBL8501386

SCHEMBL8501386

Cc1ccc(S(=O)(=O)Oc2ccccc2C2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.51
LMNA P02545 2/20 0.50
VDR P11473 1/20 0.50
MAPK1 P28482 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
GAA P10253 2/20 0.49
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
MAPT P10636 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HTT P42858 1/20 0.45
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
DHODH Q02127 1/20 0.42
CYP1A2 P05177 1/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD11B1 P28845 1/20 0.40
HSD17B3 P37058 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9542378 0.80 VDR (0.54) HTR6LMNAVDRMAPK1MEN1
SCHEMBL6938234 0.80 VDR (0.54) HTR6LMNAVDRMAPK1MEN1
SCHEMBL8501628 0.80 VDR (0.42) HTR6LMNAVDRMAPK1MEN1
SCHEMBL8500025 0.80 LMNA (0.43) HTR6LMNAVDRMAPK1MEN1
SCHEMBL10179980 0.78 HTR6 (0.63) HTR6LMNAMAPK1MEN1KMT2A
SCHEMBL8502113 0.78 CA1 (0.41)
SCHEMBL16103912 0.78 HTR6 (0.47) HTR6LMNAMAPK1MEN1KMT2A
SCHEMBL9958221 0.77 HTR6 (0.62) HTR6LMNAMAPK1MEN1KMT2A
SCHEMBL17320652 0.77 HTR6 (0.52) HTR6LMNAVDRMAPK1MEN1
SCHEMBL31572327 0.76 LMNA (0.56) HTR6LMNAVDRMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444340-B Separation and purification method for mixed dichlorotoluene by coupling rectification and crystallization 天津乐科节能科技有限公司 2023-08-25 CN claimed
WO-2017161537-A1 POLYARYLENE SULFIDE COMPOSITION WITH IMPROVED ADHESION TO METAL COMPONENTS TICONA LLC (US) 2017-09-28 WO disclosed
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed