SCHEMBL8501436

SCHEMBL8501436

CC(=O)N(CCCN(C(C)=O)C1CC(C)(C)NC(C)(C)C1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
GAA P10253 3/20 0.33
HTT P42858 1/20 0.31
POLB P06746 2/20 0.30
PIK3CD O00329 1/20 0.30
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476545 0.95 ALOX15 (0.35) ALOX15GAAHTTPOLB
SCHEMBL3299682 0.93 ALOX15 (0.37) ALOX15GAAHTTPOLBPIK3CD
SCHEMBL4417247 0.92 L3MBTL1 (0.35) ALOX15GAA
SCHEMBL23224074 0.88 ALOX15 (0.32) ALOX15
SCHEMBL10587182 0.85 ALOX15 (0.37) ALOX15GAAHTTPOLBPIK3CD
SCHEMBL13317022 0.85 ALOX15 (0.37) ALOX15GAAHTTPOLBPIK3CD
SCHEMBL15356825 0.84 ADH1C (0.41)
SCHEMBL20200263 0.84 ADH1C (0.41)
SCHEMBL13297922 0.83 ALOX15 (0.30) ALOX15
SCHEMBL9123681 0.81 ATM (0.34) ALOX15GAAHTTPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741390-B2 Coordination-polymeric triethanolamineperchlorato(triflato)metal inner complexes as additives for synthetic polymers ARTEMIS RESEARCH GMBH & CO. KG (DE) 2010-06-22 US disclosed
US-20090306257-A1 Stabilizer System for Halogenated Polymers CATENA ADDITIVES GMBH & CO. KG (DE) 2009-12-10 US disclosed
US-20090131564-A1 COORDINATION-POLYMERIC TRIETHANOLAMINEPERCHLORATO(TRIFLATO)METAL INNER COMPLEXES AS ADDITIVES FOR SYNTHETIC POLYMERS IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2009-05-21 US disclosed
US-20090105387-A1 Coordination-polymeric triethanolamineperchlorato(triflato)metal inner complexes as additives for synthetic polymers ARTEMIS RESEARCH GMBH & CO. KG (DE) 2009-04-23 US disclosed
US-5969015-A FOR ENHANCING PERFORMANCE PROPERTIES OF LUBRICANTS, HYDRAULIC FLUIDS OR METAL PROCESSING FLUIDS WITCO VINYL ADDITIVES GMBH (DE) 1999-10-19 US disclosed