Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.55 |
| ▸ | PGR | P06401 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499719 | 0.89 | NR3C1 (0.60) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL29714128 | 0.89 | NR3C1 (0.60) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL7204193 | 0.89 | NR3C1 (0.60) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL8500279 | 0.89 | NR3C1 (0.60) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL8904556 | 0.89 | NR3C1 (0.71) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL8501586 | 0.88 | NR3C1 (0.60) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL8502621 | 0.87 | NR3C1 (0.60) | NR3C1PGRCYP3A4USP2HIF1A | |
| SCHEMBL8500255 | 0.87 | CYP3A4 (0.63) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL8499360 | 0.86 | NR3C1 (0.61) | NR3C1PGRARCYP3A4USP2 | |
| SCHEMBL10352704 | 0.86 | NR3C1 (0.74) | NR3C1PGRARCYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888995-A | ANTIINFLAMMATORY AND ANTIALLERGENIC AGENTS; A NOVEL GLUCOCORTICOSTEROID | ASTRA AKTIEBOLAG (SE) | 1999-03-30 | — | — | US | disclosed |
| US-5614514-A | Steroid esters | AKTIEBOLAGET ASTRA (SE) | 1997-03-25 | — | — | US | disclosed |