Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.74 |
| ▸ | AR | P10275 | 4/20 | 0.74 |
| ▸ | PGR | P06401 | 4/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | IL5 | P05113 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543449 | 1.00 | NR3C1 (0.74) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL10352327 | 1.00 | NR3C1 (0.74) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL8500255 | 0.93 | CYP3A4 (0.63) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL9114073 | 0.92 | NR3C1 (0.64) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL8501453 | 0.86 | NR3C1 (0.55) | NR3C1ARPGRCYP3A4USP2 | |
| Halcinonide SCHEMBL24015431 | 0.85 | NR3C1 (1.00) | NR3C1ARPGRCYP3A4USP2 | |
| Halcinonide SCHEMBL5489567 | 0.85 | NR3C1 (1.00) | NR3C1ARPGRCYP3A4USP2 | |
| Halcinonide SCHEMBL8467031 | 0.85 | NR3C1 (1.00) | NR3C1ARPGRCYP3A4USP2 | |
| Halcinonide SCHEMBL7861670 | 0.85 | NR3C1 (1.00) | NR3C1ARPGRCYP3A4USP2 | |
| Halcinonide SCHEMBL5188866 | 0.85 | NR3C1 (1.00) | NR3C1ARPGRCYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164636-B1 | A PROCESS FOR THE PREPARATION OF 16,17 ACETALS OF PREGNANE DERIVATIVES AND COMPOUNDS OBTAINED THEREFROM | SICOR Società Italiana Corticosteroidi S.p.A. (IT) | 1990-09-19 | — | — | EP | claimed |