Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | MPO | P05164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127733 | 0.81 | TAAR1 (0.58) | TAAR1MPOHPGDGPR84CNR1 | |
| SCHEMBL81122 | 0.80 | LMNA (0.55) | TAAR1MPOHPGDCYP1A2CYP3A4 | |
| SCHEMBL5925035 | 0.78 | DAO (0.38) | TAAR1CNR1LMNAMEN1KMT2A | |
| SCHEMBL6564264 | 0.77 | TAAR1 (0.48) | TAAR1HPGDGPR84MEN1KMT2A | |
| SCHEMBL5544070 | 0.77 | CNR1 (0.48) | CNR1EPHX2KMT2A | |
| Hydrochloric Acid SCHEMBL7368184 | 0.75 | TAAR1 (0.67) | TAAR1MPOHPGDGPR84CNR1 | |
| SCHEMBL7425761 | 0.74 | CYP19A1 (0.38) | HPGDHIF1A | |
| SCHEMBL5649409 | 0.74 | MTNR1A (0.57) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8185928 | 0.74 | HTR2A (0.52) | TAAR1MPOCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6894181 | 0.74 | TAAR1 (0.64) | TAAR1MPOHPGDGPR84CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939398-A | ANTIATHEROSCLEROSIS AGENTS | PFIZER INC. (US) | 1999-08-17 | — | — | US | disclosed |