Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940486 | 0.86 | ATIC (0.64) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL938225 | 0.83 | ATIC (0.60) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL28773388 | 0.83 | ATIC (0.47) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL20298607 | 0.81 | ATIC (0.40) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL940609 | 0.81 | ATIC (0.40) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL850150 | 0.76 | FBP1 (0.49) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL2509891 | 0.70 | ATIC (0.46) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL4307801 | 0.69 | KDM4E (0.56) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL4954130 | 0.69 | ATIC (0.48) | ATICFBP1KDM4EBLMTSHR | |
| SCHEMBL19814010 | 0.69 | NT5E (0.41) | ATICFBP1SMN1; SMN2ADORA1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325545-B | Attenuated bacteria-based protein delivery | 巴塞尔大学 | 2024-02-09 | — | — | CN | disclosed |