Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8441340 | 0.91 | ALDH1A1 (0.48) | CA12CA2CA9ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL2484445 | 0.91 | ALDH1A1 (0.52) | CA12CA2CA9ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL8441342 | 0.89 | CA12 (0.52) | CA12CA2CA9ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL8501318 | 0.85 | CA12 (0.47) | CA12CA2CA9ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL30019534 | 0.81 | CA12 (0.43) | CA12CA2CA9ALDH1A1MAPT | |
| SCHEMBL8115 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPTRECQLMCL1KCNH3 | |
| Sulfuric Acid SCHEMBL1605645 | 0.80 | MAPT (0.59) | CA12CA2CA9ALDH1A1MAPT | |
| Acetic Acid SCHEMBL9815635 | 0.80 | MAPT (0.52) | ALDH1A1MAPTRECQLMCL1RORC | |
| Hydrochloric Acid SCHEMBL1683326 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTRECQLMCL1KCNH3 | |
| Bromide SCHEMBL28400204 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTRECQLMCL1KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998117-A | METHINE DYE CAPABLE OF BEING DECOLORED BY REACTING WITH A COLOR DEVELOPING AGENT. | KONICA CORPORATION (JP) | 1999-12-07 | — | — | US | disclosed |