Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8441340 | 0.96 | ALDH1A1 (0.48) | ALDH1A1MAPTRECQLMCL1CA12 | |
| Sulfuric Acid SCHEMBL8501569 | 0.91 | CA12 (0.44) | ALDH1A1MAPTRECQLMCL1CA12 | |
| Sulfuric Acid SCHEMBL8441342 | 0.90 | CA12 (0.52) | ALDH1A1MAPTRECQLMCL1CA12 | |
| Sulfuric Acid SCHEMBL8501318 | 0.89 | CA12 (0.47) | ALDH1A1MAPTRECQLMCL1CA12 | |
| Sulfuric Acid SCHEMBL30019534 | 0.89 | CA12 (0.43) | ALDH1A1MAPTRECQLCA12CA2 | |
| SCHEMBL8115 | 0.89 | ALDH1A1 (0.64) | ALDH1A1MAPTRECQLMCL1L3MBTL1 | |
| Sulfuric Acid SCHEMBL1605645 | 0.88 | MAPT (0.59) | ALDH1A1MAPTCA12CA2CA9 | |
| Water SCHEMBL11613453 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTRECQLMCL1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1683326 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTRECQLMCL1L3MBTL1 | |
| Bromide SCHEMBL28400204 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTRECQLMCL1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017358-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2004-08-11 | — | — | EP | claimed |
| EP-1017358-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-07-12 | — | — | EP | claimed |
| US-5939458-A | APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN | GILLETTE COMPANY, THE | 1999-08-17 | — | — | US | claimed |
| WO-1999015136-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 1999-04-01 | — | — | WO | claimed |
| CN-115368900-B | BOE etching solution for semiconductor and preparation method thereof | 昆山晶科微电子材料有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-3212183-B1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIV ROCHESTER (US) | 2019-10-02 | — | — | EP | disclosed |
| US-10028931-B2 | Synergistic compositions for treating microbial infections | UNIVERSITY OF ROCHESTER (US) | 2018-07-24 | — | — | US | disclosed |
| EP-3212183-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | University of Rochester (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2017-08-31 | — | — | US | disclosed |
| WO-2016070021-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2016-05-06 | — | — | WO | disclosed |
| US-8778631-B2 | Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system | SUTRO BIOPHARMA, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| EP-2376647-B1 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM | SUTRO BIOPHARMA INC (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-0389817-A1 | Silver halide color photographic materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-10-03 | — | — | EP | disclosed |
| EP-0330443-A2 | Cyan dye-forming couplers and photographic materials containing same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0304001-A2 | Coupler for photographic use | KONICA CORPORATION (JP) | 1989-02-22 | — | — | EP | disclosed |
| US-4774053-A | MULTILAYER-VARIOUS SPEED SILVER HALIDE EMULSION | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0276046-A2 | Light-sensitive silver halide color photographic material containing multi-functional dye | KONICA CORPORATION (JP) | 1988-07-27 | — | — | EP | disclosed |
| US-4499179-A | ABRASION RESISTANCE PROTECTIVE COATINGS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| US-4444872-A | CYAN PHENOLIC COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
| US-4299914-A | Method for forming a cyan dye image | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028931-B2 | Synergistic compositions for treating microbial infections | RNASE1, RNASEL, RNASEH1 | ALDH1A1 3822/4885MAPT 4406/4885RECQL 682/4885 |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | RNASE1, RNASEL, RNASEH1 | ALDH1A1 3822/4885MAPT 4406/4885RECQL 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.