SCHEMBL8501650

SCHEMBL8501650

CC=Cc1cccc(C(F)(F)C(F)(F)C(F)F)c1OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.37
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 6/20 0.34
MAPT P10636 5/20 0.34
MEN1 O00255 6/20 0.34
KMT2A Q03164 6/20 0.34
GAA P10253 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
HTT P42858 2/20 0.33
DHODH Q02127 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3840690 0.84 LMNA (0.40) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL8499995 0.84 MEN1 (0.38) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL3838731 0.83 LMNA (0.42) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL5672585 0.83 LMNA (0.42) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL8501647 0.80 LMNA (0.37) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL8501642 0.79 DHODH (0.35) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL3846206 0.79 LMNA (0.42) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL8501133 0.75 FFAR4 (0.38) LMNAALDH1A1MAPTMEN1KMT2A
SCHEMBL8502261 0.74 LMNA (0.43) LMNAMAPK1ALDH1A1MAPTMEN1
SCHEMBL3840930 0.74 LMNA (0.43) LMNAMAPK1ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed