SCHEMBL8501133

SCHEMBL8501133

Cc1ccc(S(=O)(=O)Oc2c(C)cc(C)cc2C(F)(F)C(F)(F)C(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.38
RAPGEF4 Q8WZA2 1/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ESR1 P03372 1/20 0.35
GAA P10253 1/20 0.35
ESR2 Q92731 1/20 0.35
CA12 O43570 2/20 0.34
CA2 P00918 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP2C19 P33261 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
AGER Q15109 1/20 0.33
CYP1A2 P05177 1/20 0.32
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8499995 0.85 MEN1 (0.38) FFAR4MEN1KMT2AESR1GAA
SCHEMBL5672439 0.84 FFAR4 (0.39) FFAR4RAPGEF4MEN1KMT2AESR1
SCHEMBL3842461 0.82 FFAR4 (0.42) FFAR4RAPGEF4MEN1KMT2AESR1
SCHEMBL3838156 0.80 FFAR4 (0.45) FFAR4RAPGEF4MEN1KMT2AESR1
SCHEMBL28584784 0.78 RAPGEF4 (0.53) FFAR4RAPGEF4MEN1KMT2AESR1
SCHEMBL8501263 0.78 RAPGEF4 (0.37) FFAR4RAPGEF4MEN1KMT2AESR1
SCHEMBL7521765 0.75 ALPL (0.40) GAAALDH1A1LMNAMAPTHTT
SCHEMBL8501650 0.75 LMNA (0.37) MEN1KMT2AESR1GAAESR2
SCHEMBL3884571 0.74 FFAR4 (0.43) FFAR4RAPGEF4MEN1KMT2AESR1
SCHEMBL10701701 0.74 KMT2A (0.44) MEN1KMT2ACA12CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed