Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13566434 | 1.00 | MEN1 (0.34) | MEN1KMT2ACA2NOS3NOS1 | |
| SCHEMBL13225466 | 0.87 | — | — | |
| SCHEMBL29219064 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL30103441 | 0.82 | CA2 (0.35) | MEN1KMT2ACA2NOS3NOS1 | |
| SCHEMBL17085285 | 0.82 | ALDH1A1 (0.38) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL17928483 | 0.81 | ALDH1A1 (0.33) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL18951901 | 0.81 | HSD17B10 (0.41) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL18951853 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL13225467 | 0.78 | ALDH1A1 (0.40) | KMT2AALDH1A1TSHR | |
| SCHEMBL12513571 | 0.77 | MGAM (0.34) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |