Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410470 | 1.00 | MEN1 (0.51) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL8410078 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8410081 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8410518 | 0.82 | RAB9A (0.55) | KMT2ALMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8410515 | 0.82 | RAB9A (0.55) | KMT2ALMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7836111 | 0.81 | MEN1 (0.56) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL11757612 | 0.79 | MEN1 (0.62) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL8410472 | 0.78 | CETP (0.53) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL21695750 | 0.76 | MEN1 (0.66) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL8413634 | 0.74 | RAB9A (0.55) | MEN1KMT2ALMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004979-A | ANGIOTENSIN II INHIBITORS; 4-((CARBOXY)ARYLOXY)-QUINOLINE DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1999-12-21 | — | — | US | disclosed |