Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410081 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8413632 | 0.84 | RAB9A (0.55) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8413634 | 0.84 | RAB9A (0.55) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL13381411 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8410518 | 0.83 | RAB9A (0.55) | ALDH1A1SMN1; SMN2KMT2AMAPTNPSR1 | |
| SCHEMBL8410515 | 0.83 | RAB9A (0.55) | ALDH1A1SMN1; SMN2KMT2AMAPTNPSR1 | |
| SCHEMBL8410470 | 0.83 | MEN1 (0.51) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8501792 | 0.83 | MEN1 (0.51) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8413637 | 0.82 | CETP (0.42) | ALDH1A1GAAMEN1KMT2ATDP1 | |
| SCHEMBL8413639 | 0.82 | CETP (0.42) | ALDH1A1GAAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |
| US-5478938-A | Antagonists for angiotensin II receptors; hypotensive, cardiotonic agents; cognitive activators | ROUSSEL UCLAF (FR) | 1995-12-26 | — | — | US | disclosed |
| US-5324839-A | Hypotensive agents, gastrointestinal and urogenital disorders | ROUSSEL-UCLAF (FR) | 1994-06-28 | — | — | US | disclosed |