Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504797 | 0.88 | CACNA1B (0.51) | MTNR1ACYP2D6CACNA1BTSHRSMPD1 | |
| SCHEMBL8504443 | 0.84 | CACNA1B (0.46) | CYP2D6CACNA1B | |
| SCHEMBL8506165 | 0.78 | S1PR1 (0.43) | ALDH1A1HPGDRAB9A | |
| SCHEMBL8502033 | 0.76 | HSD17B3 (0.45) | — | |
| SCHEMBL8501932 | 0.72 | MEN1 (0.44) | EPHX2ALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL27648733 | 0.69 | RAB9A (0.44) | CYP2D6CACNA1BTSHRMAPK1LMNA | |
| SCHEMBL11662139 | 0.69 | CYP3A4 (0.51) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL28499051 | 0.69 | CYP3A4 (0.51) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL17700298 | 0.68 | POLB (0.44) | CYP3A4ALDH1A1HPGD | |
| SCHEMBL28421485 | 0.68 | EPHX2 (0.50) | EPHX2TSHRTP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |