Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | PGR | P06401 | 5/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.57 |
| ▸ | AR | P10275 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | IL5 | P05113 | 1/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305265 | 0.87 | NR3C1 (0.76) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL19583457 | 0.87 | NR3C1 (0.76) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL18051174 | 0.87 | NR3C1 (0.76) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL19583464 | 0.87 | NR3C1 (0.76) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL8499750 | 0.87 | NR3C1 (0.74) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL8499317 | 0.86 | HIF1A (0.56) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL8503153 | 0.86 | HIF1A (0.56) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL24591950 | 0.85 | CYP3A4 (0.56) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL21153554 | 0.85 | CYP3A4 (0.56) | CYP3A4PGRNR3C1ABCB11AR | |
| SCHEMBL21152861 | 0.85 | CYP3A4 (0.56) | CYP3A4PGRNR3C1ABCB11AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888995-A | ANTIINFLAMMATORY AND ANTIALLERGENIC AGENTS; A NOVEL GLUCOCORTICOSTEROID | ASTRA AKTIEBOLAG (SE) | 1999-03-30 | — | — | US | disclosed |
| US-5614514-A | Steroid esters | AKTIEBOLAGET ASTRA (SE) | 1997-03-25 | — | — | US | disclosed |