Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.74 |
| ▸ | PGR | P06401 | 5/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.74 |
| ▸ | AR | P10275 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | IL5 | P05113 | 1/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | MMP9 | P14780 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | THPO | P40225 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666990 | 0.94 | NR3C1 (0.76) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| Flunisolide SCHEMBL2393174 | 0.89 | NR3C1 (0.79) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL20149521 | 0.87 | PGR (0.57) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL8501938 | 0.87 | CYP3A4 (0.57) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL20149149 | 0.87 | PGR (0.57) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL24591950 | 0.85 | CYP3A4 (0.56) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL21153554 | 0.85 | CYP3A4 (0.56) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL21569953 | 0.85 | NR3C1 (0.56) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL21152861 | 0.85 | CYP3A4 (0.56) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| Budesonide SCHEMBL13695912 | 0.85 | NR3C1 (1.00) | NR3C1CYP3A4PGRHIF1AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377502-B2 | Anti-MSR1 antibodies and methods of use thereof | REGENERON PHARMACEUTICALS, INC. (US) | 2022-07-05 | — | — | US | disclosed |
| US-5888995-A | ANTIINFLAMMATORY AND ANTIALLERGENIC AGENTS; A NOVEL GLUCOCORTICOSTEROID | ASTRA AKTIEBOLAG (SE) | 1999-03-30 | — | — | US | disclosed |
| US-5614514-A | Steroid esters | AKTIEBOLAGET ASTRA (SE) | 1997-03-25 | — | — | US | disclosed |
| US-4695625-A | Process for the preparation of 16,17 acetals of pregnane derivatives | SICOR SOCIETA ITALIANA CORTICOSTEROIDI S.P.A. (IT) | 1987-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377502-B2 | Anti-MSR1 antibodies and methods of use thereof | CD47, MSR1, LDLR | NR3C1 1628/4885CYP3A4 4497/4885PGR 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.