Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503494 | 0.98 | MAPT (0.49) | MAPTTP53TSHRSMN1; SMN2PLA2G4B | |
| SCHEMBL12000272 | 0.76 | MAPK1 (0.50) | TP53TSHRSMN1; SMN2PLA2G4B | |
| SCHEMBL9475743 | 0.76 | TP53 (0.51) | TP53TSHRSMN1; SMN2PLA2G4BNR5A1 | |
| SCHEMBL9475612 | 0.76 | TP53 (0.51) | TP53TSHRSMN1; SMN2PLA2G4BNR5A1 | |
| SCHEMBL13439692 | 0.76 | LTA4H (0.50) | MAPTSMN1; SMN2 | |
| SCHEMBL9016858 | 0.73 | NR5A1 (0.61) | MAPTTP53TSHRSMN1; SMN2PLA2G4B | |
| SCHEMBL10013798 | 0.73 | NR5A1 (0.61) | MAPTTP53TSHRSMN1; SMN2PLA2G4B | |
| SCHEMBL13227405 | 0.73 | NR5A1 (0.61) | MAPTTP53TSHRSMN1; SMN2PLA2G4B | |
| SCHEMBL13612295 | 0.72 | DGKA (0.59) | TP53TSHRPLA2G4BNR5A1L3MBTL1 | |
| SCHEMBL13572570 | 0.72 | DGKA (0.54) | MAPTTP53TSHRPLA2G4BNR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |