Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | DRD1 | P21728 | 3/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504189 | 0.86 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3DRD1 | |
| SCHEMBL8505693 | 0.82 | DRD1 (0.66) | SLC6A2SLC6A4SLC6A3DRD1DRD5 | |
| SCHEMBL8504024 | 0.78 | DRD1 (0.53) | SLC6A2SLC6A4SLC6A3DRD1 | |
| SCHEMBL8504160 | 0.78 | DRD1 (0.53) | SLC6A2SLC6A4SLC6A3DRD1DRD5 | |
| SCHEMBL8504152 | 0.76 | DRD1 (0.55) | SLC6A2SLC6A4SLC6A3DRD1 | |
| Hydrochloric Acid SCHEMBL7267588 | 0.75 | DRD1 (0.52) | SLC6A2SLC6A4SLC6A3DRD1DRD5 | |
| SCHEMBL4301574 | 0.73 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3DRD1 | |
| SCHEMBL8506683 | 0.73 | DRD1 (0.55) | SLC6A2SLC6A4SLC6A3DRD1 | |
| SCHEMBL29602922 | 0.73 | DRD1 (1.00) | SLC6A2SLC6A4SLC6A3DRD1DRD5 | |
| SCHEMBL5138043 | 0.73 | DRD1 (1.00) | SLC6A2SLC6A4SLC6A3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688320-B1 | TRICYCLIC BENZODIAZEPINS, THEIR USE AND PREPARATION | NOVO NORDISK AS (DK) | 1999-05-06 | — | — | EP | claimed |
| EP-0688320-A1 | TRICYCLIC BENZODIAZEPINS, THEIR USE AND PREPARATION | NOVO NORDISK A/S (DK) | 1995-12-27 | — | — | EP | claimed |
| WO-1994020472-A1 | HETEROCYCLIC COMPOUNDS, THEIR USE AND PREPARATION | NOVO NORDISK A/S (DK) | 1994-09-15 | — | — | WO | claimed |
| EP-0688320-B1 | TRICYCLIC BENZODIAZEPINS, THEIR USE AND PREPARATION | NOVO NORDISK AS (DK) | 1999-05-06 | — | — | EP | disclosed |
| EP-0688320-A1 | TRICYCLIC BENZODIAZEPINS, THEIR USE AND PREPARATION | NOVO NORDISK A/S (DK) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020472-A1 | HETEROCYCLIC COMPOUNDS, THEIR USE AND PREPARATION | NOVO NORDISK A/S (DK) | 1994-09-15 | — | — | WO | disclosed |