Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL8505553 | 0.96 | TSHR (0.52) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL29531388 | 0.87 | CYP3A4 (0.52) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL5069944 | 0.87 | CYP3A4 (0.52) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL29525350 | 0.80 | LMNA (0.68) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL3908136 | 0.80 | LMNA (0.68) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL335929 | 0.80 | ALDH1A1 (0.52) | HPGDHSD17B10ALOX15KDM4EALDH1A1 | |
| SCHEMBL29693542 | 0.80 | ALDH1A1 (0.52) | HPGDHSD17B10ALOX15KDM4EALDH1A1 | |
| SCHEMBL6754597 | 0.79 | NPC1 (0.44) | TSHRLMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL21694738 | 0.79 | ALDH1A1 (0.58) | TSHRHPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL27537269 | 0.79 | LMNA (0.52) | TSHRLMNAHPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945457-A | Process for preparing biologically compatible polymers and their use in medical devices | A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCE (RU) | 1999-08-31 | — | — | US | disclosed |
| WO-1999016475-A2 | PROCESS FOR PREPARING BIOLOGICALLY COMPATIBLE POLYMERS AND THEIR USE IN MEDICAL DEVICES | A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESISRUSSIAN ACADEMY OF SCIENCE (US) | 1999-04-08 | — | — | WO | disclosed |