SCHEMBL6754597

SCHEMBL6754597

C=CC(=O)OC(=O)c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
PLK1 P53350 1/20 0.40
PLK2 Q9NYY3 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
TSHR P16473 1/20 0.40
HPGD P15428 1/20 0.40
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531388 0.87 CYP3A4 (0.52) NPC1MAPTLMNACYP3A4TSHR
SCHEMBL5069944 0.87 CYP3A4 (0.52) NPC1MAPTLMNACYP3A4TSHR
SCHEMBL30579929 0.86 MEN1 (0.43) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL27922879 0.85 ALDH1A1 (0.36) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL1247158 0.84 NPC1 (0.43) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL29436920 0.82 NPC1 (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL777261 0.82 NPC1 (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL27589207 0.82 ALDH1A1 (0.41) NPC1RAB9AMEN1KMT2ALMNA
SCHEMBL27537269 0.82 LMNA (0.52) KMT2AMAPTLMNACYP3A4TSHR
SCHEMBL644784 0.81 TSHR (0.68) LMNACYP3A4TSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746227-A Fluorine-containing block copolymer and use thereof 广州立邦涂料有限公司 2023-03-07 CN claimed
CN-115746227-A Fluorine-containing block copolymer and use thereof 广州立邦涂料有限公司 2023-03-07 CN disclosed
US-20140275049-A1 SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS ELI LILLY AND COMPANY 2014-09-18 US disclosed
WO-2013066640-A1 SUBSTITUTED PYRAZOLE ANALOGUES AS RAR ANTAGONISTS ELI LILLY AND COMPANY (US) 2013-05-10 WO disclosed
US-6806042-B2 PHOTOGRAPHIC FILMS COMPRISNG SUPPORTS HAVING RED, GREEN AND BLUE SENSITIVE SILVER HALIDE EMULSIONS, AND CYAN, MAGENTA AND YELLOW COUPLERS RESPECTIVELY; IMAGES AGFA-GEVAERT (BE) 2004-10-19 US disclosed
US-20040023171-A1 Colour photographic print material AGFA-GEVAERT N.V. (BELGIUM) 2004-02-05 US disclosed
EP-1380893-A2 Colour photographic print material Agfa-Gevaert (BE) 2004-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275049-A1 SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS RARB, RARA, RARG NPC1 3702/4885RAB9A 1378/4885MEN1 4858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.